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Centre

Central Animal Facility

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About the Centre

[sustainability composite]National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences set up under the aegis of Ministry of Chemicals and Fertilizers, Govt. of India.

The Central Animal Facility (CAF), NIPER is established with the state- of- art technology in a double storied building with a design of ‘Two-way corridor system’ to minimize the cross contamination. Our establishment is registered with CPCSEA, Ministry of Environment and Forest, Government of India (108/1999/CPCSEA) for the breeding and research purpose. The different species of small laboratory animals like mice, rats, hamsters, gerbils, guinea pigs and rabbits are being bred in-house and maintained mainly to cater the needs of investigators for the various research purposes within the institute.

Under certain circumstances of surplus availability, the animals are also supplied on request to the outside CPCSEA registered establishments at reasonable rates on non-profit basis purely for the breeding and research purposes only.

Each species of animals is housed in barrier maintained individual rooms to avoid inter-species cross infection. The animals are maintained under controlled environmental conditions (temperature (22� 2�C), relative humidity (50 � 5 %), 12:12 h light and dark cycle with 100 % of fresh air exchange in animal rooms) with uninterrupted power supply. The macro- and micro- environment around the animals are maintained as per the CPCSEA guidelines. Separate building for holding of infective and non-infective experimental animals is available. A high degree of hygienic conditions is being maintained. Regular disinfection of animal rooms and cleaning and sterilization of cages, water bottles, bedding etc are practiced. Heavy duty steam sterilizers have been provided for sterilization of all materials entering into animals rooms. In addition to the conventionally maintained colonies, CAF do have the animal isolator and individually ventilated caging systems (IVC) for breeding and maintaining the animal colonies in SPF environment.

Periodic health monitoring of the animals is carried out to ascertain the heath status of the animals. In addition, feed and water analysis are carried out periodically for assessing their quality and microbiological contamination. The various records of the inbred and out bred animals are maintained through in-house developed specialized software system (CAFMS) in addition to manual record keeping. Waste disposal is carried out through environment friendly incinerator. A team of well qualified veterinarian/scientist and technical assistants, who are experienced and trained in modern methods of animal care, breeding and husbandry, manage this facility. The routine works at CAF are carried out as per the standard operating procedures adopting GLP principles to achieve the high quality supply of the animals for the biomedical/pharmaceutical research and development.