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Departments

Department of Pharmaceutics

  1. About the Department
  2. Faculty
  3. Staff
  4. Research Facilities
  5. Contact Information

pe@niper.ac.in

Drug development has become increasingly complex, time consuming and expensive. As a result there is an increased focus on making clinically established drugs perform better therapeutically in terms of efficacy, safety and improved patient compliance by designing novel and patentable technologies or delivery systems. This has led to a paradigm shift in drug delivery technologies from conventional dosage forms to controlled release and sophisticated delivery systems. These systems are based on the concepts of biopharmaceutics and pharmacokinetic driven by pharmacodynamic activity and therapeutic needs. The emergence of the Biopharmaceutic Classification System (BCS) based on the two tenets of absorption namely solubility and permeability has further simplified drug development program form a regulatory perspective. About 20 drugs, which are not only of clinical significance but also, model drugs representing various classes were chosen by the department to carry out research and projects in the area of conventional and novel drug delivery systems, biopharmaceutics and pharmacokinetic evaluation, bioavailability and bioequivalence testing, preformulation, formulation development and stability testing.

The department of pharmaceutics is one of the key departments of the Institute. It is equipped with state of the art facilities to undertake research in drug development and delivery. More recently, the department has initiated research on Biomaterials and Nanotechnology. In the frontier area of Biomaterial research, the focus will be for synthesis and characterization of new biodegradable polymer, their formulations for various drug delivery systems, to improve surface biocompatibility of medical devices and their invitro/invivo evaluation. To strengthen our research potential, nanotechnolgy will be utilized to prepare effective carriers to deliver the drugs at diseases targets and effort will be taken to initiate gene delivery program in our department.

Presently engaged in research projects

The department is presently engaged in research projects on :

  • Pre-formulation profiling, crystal engineering and pharmaceutical material characterization
  • Solid state manipulation of drug products to enhance solubility and oral bioavailability
  • Targeted anticancer drug delivery using multifunctional nanocarriers
  • Lipid drug/ polymer drug/ drug-polymer-drug conjugates for effective drug delivery
  • Oral delivery of injection only drugs molecules including proteins/ peptides and vaccine antigens
  • Targeted DNA/ gene delivery
  • Topical and transdermal drug delivery
  • Macromolecular Lipid Drug/ Polymer Dual Drug conjugates
  • In vitro cytotoxicity of anticancer drug loaded nanocarriers in various cancer cell lines
  • Intracellular trafficking of nano-carrier systems through co-localization experiments
  • Caco-2 cells permeability of Nanocarriers

Projects Completed and Ongoing

Projects Completed and Ongoing :

  • Development and evaluation of transdermal systems including Iontophoretic delivery of peptide and protein drugs
  • Pharmacokinetic-based controlled release dosage forms (drugs under investigation: nifedipine, diltiazem, azithromycin isosorbide mononitrate, glipizide, ketorolac, salbutamol, cephalosporin and cyclosporin)
  • Biomaterials for improving surface biocompatibility of medical devices
  • Synthesis and characterization of new biodegradable polymers for delivery of anticancer drugs
  • Design of biodegradable nanoparticles for pharmaceutical applications
  • Development and evaluation of nanoparticles for delivery of estradiol, antioxidants and insulin

Pharmaceutics Research Facilities

The department is presently engaged in research projects on :

  • Animal Cell Culture Facility
  • Confocal Laser Scanning Microscope
  • Scanning Electron Microscope
  • Atomic Force Microscope
  • Real Time In Vivo Optical Imaging
  • Freeze Dryer
  • Ultracentrifuge
  • High Performance Liquid Chromatography
  • 8-station Franz Diffusion Cells
  • Differential Scanning Calorimetry
  • Cone and Plate Viscometer
  • Probe Sonicator
  • Zetasizer
  • Hot stage Microscopy
  • Dielectric Spectroscopy
  • Contact Angle Measurement
  • Instrumented Rotary Table Press with Portable Press Analyzer
  • Spray Dryer
  • Isothermal Nanocalorimeter
  • Surface Area Analyzer
  • True Density Meter
  • Tablet and Pellet Coaters

Faculty

Prof. Arvind K Bansal

(M. Pharm., Ph. D.)

Designation : Head of Department Email: akbansal@niper.ac.in Area of Specialization : Expertise in solid-state pharmaceutics and pharmaceutical development, advanced drug delivery employing solid-state manipulation.

Dr. Sanyog Jain

(M. Pharm., Ph. D.)

Designation : Associate Professor Email: sanyogjain@niper.ac.in sanyogjain@rediffmail.com Area of Specialization : Expertise in the field of novel or advanced drug delivery systems, nano-medicines employing nano-carrier based strategies and nanotechnology.

Dr. Abhay T. Sangamwar

(M. Pharm., Ph. D.)

Designation : Assistant Professor Email: abhays@niper.ac.in Area of Specialization : Integration of computational tools with experimental tools in the area of pre-formulation and drug delivery.

Staff

Mr. Gunjan Kohli

Designation : Technical Assistant Email: gunjan@niper.ac.in kohlig75@gmail.com

Mr. Rahul R Mahajan

Designation : Technical Assistant Email: rahulm@niper.ac.in rrmahajan05@gmail.com

Mr. Mahesh Chand

Designation : Technical Assistant Email: kashyap@niper.ac.in kashyap.niper@gmail.com

Mr. Sanjaya K Samal

Designation : Junior Technical Assistant Email: sanjaya.niper@gmail.com

Mrs. Aarti Chhetri

Designation : Stenographer of Department Email: aarti@niper.ac.in

Contact Information

Prof. Arvind K Bansal, M. Pharm., Ph. D.

Department of Pharmaceutics

akbansal@niper.ac.in

  0172 221 2054